HIV-1 Group O Infection in Cameroon, 1986 to 1998

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HIV-1 Group O Infection in Cameroon, 1986 to 1998
We report a survey of HIV-1 group O infection in Cameroon during 1986 to 1998. The prevalence of HIV-1/O decreased from 0.6% to 0.4%, while HIV-1/M increased from 19.2% to 31.5% from 1994 to 1998. We concluded that HIV-1/O infection is stable in Cameroon and may be declining slightly.

HIV-1 group O (HIV-1/O) was first identified in Cameroon in 1994 (1), raising concern about the emergence of a new HIV-1 variant, with implications for public health and blood safety. Anti-HIV-1/O antibodies are weakly detected by some HIV-1 screening tests, and the natural resistance of most HIV-1/O strains to nonnucleoside inhibitors of reverse transcriptase limits their use in preventing vertical transmission.

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