Exercise vs. Usual Care in Stable Immune Mediated Neuropathy
Exercise vs. Usual Care in Stable Immune Mediated Neuropathy
This is the first randomised controlled trial to compare the efficacy and cost-effectiveness of a tHEP with advice about exercise and usual care in IN. A feasibility study by this research group provided evidence that tailored home exercise is acceptable to individuals with IN and that participation in a tHEP was associated with significant improvements in activity limitation, fatigue, quality of life and mood in an uncontrolled study.
There are two key strengths of the current RCT: firstly, the integrity and quality of the intervention delivery is enhanced by having one physiotherapist to conduct all assessments and exercise prescription that includes the use of behavioural change techniques to facilitate uptake and adherence to the exercise, and second the qualitative analysis of interviews with participants after completion of the intervention, and the cost-effectiveness and cost-utility analyses, will provide valuable information regarding the acceptability and feasibility of the intervention as a potential standard of care for individuals experiencing activity limitation and participation restriction as a result of stable IN.
Discussion
This is the first randomised controlled trial to compare the efficacy and cost-effectiveness of a tHEP with advice about exercise and usual care in IN. A feasibility study by this research group provided evidence that tailored home exercise is acceptable to individuals with IN and that participation in a tHEP was associated with significant improvements in activity limitation, fatigue, quality of life and mood in an uncontrolled study.
There are two key strengths of the current RCT: firstly, the integrity and quality of the intervention delivery is enhanced by having one physiotherapist to conduct all assessments and exercise prescription that includes the use of behavioural change techniques to facilitate uptake and adherence to the exercise, and second the qualitative analysis of interviews with participants after completion of the intervention, and the cost-effectiveness and cost-utility analyses, will provide valuable information regarding the acceptability and feasibility of the intervention as a potential standard of care for individuals experiencing activity limitation and participation restriction as a result of stable IN.
Source...