Summary of Acetylsalicylic Acid
Acetylsalicylic Acid, also known by trade name Aspirin, is an acetyl derivative of salicylic acid that is a white, crystalline, weakly acidic substance, with melting point 137 C. Its CAS NO is 50-78-2.
It belongs to a class called salicylates compound, this compound in the plant where it is. 400 BC Hippocrates (Hippocrates, 460 BC to 360 doctors of ancient Greece, the Bank said the father of medicine), have used willow bark to relieve pain, willow bark contains salicylates compounds. In 1853, Charles Where Gerhardt (Charles von Gerhardt, German chemist) was first synthesized acetylsalicylic acid. In 1893, Felix Hoffman, another German doctor, discovered with the lowest cost method of mass production of this drug. In 1899, this drug was first to begin selling the name Acetylsalicylic acid. It has been trademark, until 1921 the court declared this medicine is acetylsalicylic acid name drugs, because it has been so widely used.
Today, Acetylsalicylic Acid is one of the most widely used medications in the world, estimated 40,000 tones of Acetylsalicylic Acid being consumed each year. In countries where Acetylsalicylic Acid is a registered trademark owned by Bayer, the generic term is acetylsalicylic acid (ASA).
It`s most common use is to relieve headaches as well as muscle & joint pain. Acetylsalicylic Acid interferes with the bodys synthesis of specific POSTAGLANDINS. These compounds are produced by almost every tissue in the body and control the substances involved in the transmission of nerve impulses which participate in the body`s defences against infection. Postaglandins have been shown to bring on fever and play a major role in inflammation.
This mdeicine also has an antiplatelet effect by inhibiting the production of thromboxane, which under normal circumstances binds platelet molecules together to create a patch over damaged walls of blood vessels. Because the platelet patch can become too large and also block blood flow, locally and downstream, aspirin is also used long-term, at low doses, to help prevent heart attacks, strokes, and blood clot formation in people at high risk of developing blood clots. It has also been established that low doses of aspirin may be given immediately after a heart attack to reduce the risk of another heart attack or of the death of cardiac tissue. Aspirin may be effective at preventing certain types of cancer, particularly colorectal cancer.
The main undesirable side effects of aspirin taken by mouth are gastrointestinal ulcers, stomach bleeding, and tinnitus, especially in higher doses. In children and adolescents, aspirin is no longer indicated to control flu-like symptoms or the symptoms of chickenpox or other viral illnesses, because of the risk of Reye's syndrome.
For many people this medicine has side effects: heartburn, indigestion, nausea and vomiting. Acetylsalicylic acid can irritate the stomach membrane, can cause internal bleeding. Allergic reactions include abdominal pain, itching, swelling of the face and throat. Long-term use can cause iron deficiency, stomach ulcers and gastrointestinal bleeding.
It belongs to a class called salicylates compound, this compound in the plant where it is. 400 BC Hippocrates (Hippocrates, 460 BC to 360 doctors of ancient Greece, the Bank said the father of medicine), have used willow bark to relieve pain, willow bark contains salicylates compounds. In 1853, Charles Where Gerhardt (Charles von Gerhardt, German chemist) was first synthesized acetylsalicylic acid. In 1893, Felix Hoffman, another German doctor, discovered with the lowest cost method of mass production of this drug. In 1899, this drug was first to begin selling the name Acetylsalicylic acid. It has been trademark, until 1921 the court declared this medicine is acetylsalicylic acid name drugs, because it has been so widely used.
Today, Acetylsalicylic Acid is one of the most widely used medications in the world, estimated 40,000 tones of Acetylsalicylic Acid being consumed each year. In countries where Acetylsalicylic Acid is a registered trademark owned by Bayer, the generic term is acetylsalicylic acid (ASA).
It`s most common use is to relieve headaches as well as muscle & joint pain. Acetylsalicylic Acid interferes with the bodys synthesis of specific POSTAGLANDINS. These compounds are produced by almost every tissue in the body and control the substances involved in the transmission of nerve impulses which participate in the body`s defences against infection. Postaglandins have been shown to bring on fever and play a major role in inflammation.
This mdeicine also has an antiplatelet effect by inhibiting the production of thromboxane, which under normal circumstances binds platelet molecules together to create a patch over damaged walls of blood vessels. Because the platelet patch can become too large and also block blood flow, locally and downstream, aspirin is also used long-term, at low doses, to help prevent heart attacks, strokes, and blood clot formation in people at high risk of developing blood clots. It has also been established that low doses of aspirin may be given immediately after a heart attack to reduce the risk of another heart attack or of the death of cardiac tissue. Aspirin may be effective at preventing certain types of cancer, particularly colorectal cancer.
The main undesirable side effects of aspirin taken by mouth are gastrointestinal ulcers, stomach bleeding, and tinnitus, especially in higher doses. In children and adolescents, aspirin is no longer indicated to control flu-like symptoms or the symptoms of chickenpox or other viral illnesses, because of the risk of Reye's syndrome.
For many people this medicine has side effects: heartburn, indigestion, nausea and vomiting. Acetylsalicylic acid can irritate the stomach membrane, can cause internal bleeding. Allergic reactions include abdominal pain, itching, swelling of the face and throat. Long-term use can cause iron deficiency, stomach ulcers and gastrointestinal bleeding.
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