New Stroke Management Guidelines: A Quick and Easy Guide
New Stroke Management Guidelines: A Quick and Easy Guide
The Basics:
• Aspirin within 24-48 hours
• Other antiplatelet agents not recommended
The Bottom Line: Aspirin remains the only antiplatelet agent for which data support use in acute stroke, although trials with other agents are in progress.
Unchanged: Oral aspirin is recommended for most patients within 24-48 hours of initial symptoms; however, it is not a suitable substitute for other acute stroke interventions, including rtPA.
Revised: Clopidogrel's usefulness is not well established, and the use of IV antiplatelet drugs that inhibit the glycoprotein IIb/IIIa receptor is not recommended. Adjunctive aspirin, or other antiplatelet therapies, within 24 hours of IV fibrinolysis are also not recommended.
New: The efficacy of glycoprotein IIb/IIIa inhibitors tirofiban and eptifibatide is not well-established.
Antiplatelet Agents
The Basics:
• Aspirin within 24-48 hours
• Other antiplatelet agents not recommended
The Bottom Line: Aspirin remains the only antiplatelet agent for which data support use in acute stroke, although trials with other agents are in progress.
Unchanged: Oral aspirin is recommended for most patients within 24-48 hours of initial symptoms; however, it is not a suitable substitute for other acute stroke interventions, including rtPA.
Revised: Clopidogrel's usefulness is not well established, and the use of IV antiplatelet drugs that inhibit the glycoprotein IIb/IIIa receptor is not recommended. Adjunctive aspirin, or other antiplatelet therapies, within 24 hours of IV fibrinolysis are also not recommended.
New: The efficacy of glycoprotein IIb/IIIa inhibitors tirofiban and eptifibatide is not well-established.
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