Overdose

• Overdosing on Lortab is a possible side effect, according to MedlinePlus. Symptoms of overdose include extreme sleepiness, cold, clammy or blue skin, shallow breathing and slowed or rapid heartbeat.
  
  

Allergic Reaction

• Some people are allergic to Lortab, according to MedlinePlus. Symptoms include hives, wheezing, itching, a rash or difficulty breathing.
  
  

Serious Side Effects

• Other serious side effects requiring immediate medical attention can result, according to MedlinePlus. These include chest pain or tightness and narrowed pupils of the eyes.
  
  

Emotional Side Effects

• Lortab can cause disturbing but usually not life-threatening emotional side effects, according to MedlinePlus. These include euphoria, depression, anxiety and slowed thinking.
  
  

Physical Side Effects

• Physical side effects that usually do not require emergency medical help are also possible with hydrocodone use, according to MedlinePlus. These include nausea, difficulty urinating, constipation and dizziness.