Zollinger-Ellision syndrome is the name given to a condition in which tumors form in the upper intestine or pancreas. Hormones are emitted by the tumors which cause increased acid production in the stomach, which leads to peptic ulcers. This syndrome is very rare – and less than one percent of duodenal ulcers are a result of Zollinger-Ellison syndrome. Generally, this condition is more commonly seen in people over 50 years of age; however, this disease can occur at any period in life.

Symptoms of this condition are similar to those of peptic ulcer. For instance, common symptoms include heartburn and a burning or aching sensation in the upper abdomen. Addition symptoms include diarrhea, weakness, nausea, vomiting, digestive tract bleeding and unintentional weight loss.

The exact cause for Zollinger-Ellison syndrome is still unknown. However, if you should experience any of the symptoms listed above for a persistent period, you should see your doctor. If you are using over-the-counter medication such as antacids, you may be masking your symptoms and it could delay an accurate diagnosis from your physician.

Normally, diagnosis of this condition can be accomplished with a patient history, blood tests, endoscopy of the upper gastrointestinal tract, imaging studies and ultrasound.

Treatment for Zollinger-Ellison syndrome is comprised of medication, which reduces acid and helps ulcers to heal. Medications such as proton pump inhibitors are usually the recommended treatment. They work by reducing acid build-up through blocking the action of cells that pump acid. In some cases, surgery may be needed to remove the tumors. Your physician will be able to explain this process in detail, which is why it is important to see your doctor if your symptoms persist.