Diagnosis, Treatment and Prevention of Ankle Sprains

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Diagnosis, Treatment and Prevention of Ankle Sprains

Materials and Methods


The recommendations set in this guideline are, if available, based on evidence from published scientific research. Relevant articles were searched in the Cochrane Library, Medline and Embase. The full search strategy is available upon request. The language was limited to Dutch, English, German, French, Danish, Norwegian and Swedish. In search for additional information, all reference lists of the included articles were checked manually. Articles published between January 1996 and March 2009 were enclosed. The quality of included articles was assessed by epidemiologists on the basis of 'evidence-based guideline development' – assessment forms and classified in various levels in order of probative and scientific value (Table 1 and Table 2). The results based on the evidence from literature are presented in categories with levels of evidence of the conclusions included. In formulating the final recommendations, the guideline committee also took other aspects into account, such as potential harm of the interventions, patients' perspective, costs and organisational aspects. If the guideline committee decided that based on current evidence a positive recommendation was not opportune, this was stated as well. So, recommendations were evidence-based and consensus-based. Below, the evidence and discussion among the committee members are summarised, and the final recommendations presented in italics.

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