Trecator SC (ethionamide) dosing, indications, interactions, adverse effects, and more , , , Trecator SC (ethionamide) dosing, indications, interactions, adverse effects, and more, , , , , , , , , , , , , , , , , Edition:EnglishFrançaisDeutsch, Search, , No Results, News & Perspective, Drugs & Diseases, CME & Education, Log In, Register, , , , , https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cDovL3JlZmVyZW5jZS5tZWRzY2FwZS5jb20vZHJ1Zy90cmVjYXRvci1zYy1ldGhpb25hbWlkZS0zNDI2OTU=, , , processing.... , , , , , ethionamide (Rx)Brand and Other Names:Trecator, Classes: Antitubercular Agents, , Dosing & Uses, Interactions, Adverse Effects, Warnings, Pregnancy, Pharmacology, Images, Patient Handout, Formulary, Dosing & Uses, AdultPediatric, Dosage Forms & Strengths, , tablet, , 250mg, , , more... Tuberculosis, Active, , 15-20 mg/kg/day PO, , No more than 1000 mg/day, , Renal Impairment, , CrCl <10 mL/min: decrease dose 50%, , Administration, , Part of multi-drug regimen; not first-line treatment, , Take with food, , Other Information, , Monitor: baseline & periodic LFTs, TFTs, glucose, , Dosage Forms & Strengths, , tablet, , 250mg, , , more... Tuberculosis, Active, , 10-20 mg/kg/day divided BID/TID PO OR, , 15 mg/kg PO qD, , No more than 1000 mg/day, , Renal Impairment, , CrCl <10 mL/min: decrease dose 50%, , Administration, , Part of multi-drug regimen; not first-line treatment, , Take after meals, , Other Information, , Monitor: baseline & periodic LFTs, TFTs, glucose, , Interactions, Interaction Checker, ethionamide and , No Results, No Interactions Found, Interactions Found, Contraindicated, Serious - Use Alternative, Significant - Monitor Closely, Minor, Sort by : , , Adverse Effects, , >10%, , Disorder of gastrointestinal tract (50%), , , Frequency Not Defined, , , , Postural hypotension, , Depression, , Dizziness, , Drowsiness, , Headache, , Peripheral neuropathy, , Psychosis, , Photosensitivity, , Rash, , Excessive salivation, , Gynecomastia, , Hypoglycemia, , Impotence, , Anorexia , , Dyspepsia , , Diarrhea, , Nausea, , Metallic taste, , Vomiting, , Thrombocytopenia, , Elevated liver transaminases, , Hepatitis, , Optic neuritis, , Visual changes, , , Warnings, , Contraindications, , Hypersensitivity to ethionamide, , Severe hepatic dysfunction, , , Cautions, , Diabetes mellitus, thyroid disease, hepatic impairment, , HIV pts may have malabsorption syndrome, , , Pregnancy & Lactation, , Pregnancy Category: C, , Lactation: excretion in milk unknown; use with caution, , Pregnancy Categories, A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk. B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA:Information not available. more... Pharmacology, , Metabolism: liver, , Excretion: kidney, , Mechanism of Action, , Bacteriostatic or bactericidal, , , Images, , Patient Handout, Print w/ Office Info, Print w/out Office Info, , Formulary, FormularyPatient Discounts, To view formulary information first create a list of plans. Your list will be saved and can be edited at any time. Create Your List of Plans, Adding plans allows you to:, View the formulary and any restrictions for each plan. Manage and view all your plans together – even plans in different states. Compare formulary status to other drugs in the same class. Access your plan list on any device – mobile or desktop. The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information. View explanations for tiers and restrictions, Tier, Description, 1, This drug is available at the lowest co-pay. Most commonly, these are generic drugs. 2, This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs. 3, This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs. 4, This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products. 5, This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products. 6, This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products. NC, NOT COVERED, – Drugs that are not covered by the plan. Code, Definition, PA, Prior Authorization, Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription. , QL, Quantity Limits, Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered. , ST, Step Therapy, Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription. , OR, Other Restrictions, Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription. , Done, Add or Remove Plans, Plans for , Select State: , Alabama, Alaska, Arizona, Arkansas, California, Colorado, Connecticut, Delaware, District of Columbia, Florida, Georgia, Hawaii, Idaho, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Montana, Nebraska, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, , Puerto Rico, Rhode Island, South Carolina, South Dakota, Tennessee, Texas, Utah, Vermont, Virginia, Washington, West Virginia, Wisconsin, Wyoming, Non-Medicare PlansMedicare Plans, Select a box to add or remove a plan. close, Select a class to view formulary status for similar drugs, CLOSE, Additional Offers, CLOSE, Email to Patient, From:, To:, The recipient will receive more details and instructions to access this offer. By clicking send, you acknowledge that you have permission to email the recipient with this information. Send, CLOSE, Email Forms to Patient, From:,