Name: Copper Sulfate

Other Names:  Bluestone,  blue vitriol, copper sulphate, cupric sulfate

Action: Anti-parasitic, fungicide, herbicide, and pesticide.

History & Uses:  Copper sulfate is inorganic compound that combines sulfur with copper that has been registered for use in the United States since 1956. It is widely used in agriculture as a fungicide in fruit and vegetable farming. It is available as a dust, wettable powder, and as a liquid.

Copper sulfate is also used for pyrotechnics, to create brilliant blue fireworks. It has also been used as a dye and for electroplating processes. In aquaculture it is used as an algicide and to treat parasites. It is not safe for use with any invertebrates. Conditions that copper sulfate is used to treat include the following:

• Ichthyophthirius multifilis - Small white spots resembling sand, fish scratches against objects. Prophylactic for quarantine tanks.
• Protozoan Infections.
• Removal of Snails.

Products Containing Copper Sulfate:

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Mardel Coppersafe  

Manufacturers Directions for Use: Use 5 ml for 4 gallons of water. Loosen measuring chamber cap and squeeze bottle to fill to desired level. One application treats water for one month. DO NOT overdose.

Active Ingredients: Chelated Copper Sulfate.

Precautions: CopperSafe may be harmful to plants and some snails. If possible, remove plants and invertebrates without an exoskeleton from the aquarium.

Otherwise, treat fish in a separate quarantine tank. Keep out of reach of children. For aquarium use only.

CopperSafe is intended for the exclusive use with ornamental fish and/or ornamental organisms and is not intended for use with humans or fish for human consumption.

Benefit: CopperSafe is a chelated copper compound that is used for the treatment of infections of Ick, Flukes (Gyrodactylus), Anchor Worms, Velvet/Protozoan diseases and other external parasites.

CopperSafe, when used as directed, maintains a total copper level of 1.5 ppm to 2.0 ppm in the water. CopperSafe remains active for over one month in the aquarium. Levels of 0.3 ppm free copper are recommended in the literature for therapeutic use, but with Coppersafe, the levels of free copper will be measured at 1.5 ppm to 2.0 ppm. This level of copper can be used in the treatment of fish due to Coppersafe's unique chelating agent. The chelating agent binds with the copper making it nontoxic to fish but effective against parasites. CopperSafe does not discolor the water and will not interfere with the biological filter

Use: CopperSafe should be used when a diagnosis of the fish's illness indicates the presence of Ick, Flukes (Gyrodactylus), Anchor Worms, Velvet/ Protozoan Diseases and other external freshwater parasites.

NOTE: CopperSafe may cause an adverse reaction with some sensitive invertebrates. Invertebrates without an exoskeleton such as jellyfish and anemones should be removed before treatment. CopperSafe may be harmful to plants, amphibians, and snails.

A chelated or total copper test kit is required to measure CopperSafe. Coppersafe may cause inaccurate free copper readings when using certain test kits. All readings should be based on the total copper or chelated copper results and not the free copper results.

Coppersafe is safe to use with UV Sterilizers, Protein Skimmers, Wet/Dry and Diatomaceous earth filters. After treatment, Coppersafe can be removed from the aquarium by water changes, fresh activated carbon or other chemical filtration resins/pads.

Comes in 100 ml, 250 ml, 500 ml,  2 liter and 20 liter sizes.

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Seachem Cupramine 

Manufacturers Directions for Use: Remove all invertebrates. Turn off UV sterilizer; remove chemical filtration. If the bottle has a dropper cap, use 20 drops (1 mL) per 40 L (10.5 gallons) the first day, wait 48 hours, then repeat. On non-dropper caps, each inner ring is 1 mL. In freshwater, use half dose. Final copper concentration is 0.5 mg/L (0.25 mg/L in freshwater). Leave at this concentration for 14 days. Do not re-dose without testing levels using MultiTest Copper (DFS# 4343010).

Do not use in conjunction with any other medication. If tank has ever been treated with an ionic copper (e.g. copper chloride, sulfate or citrate), test copper level after initial dosing. Although most fish tolerate Cupramine to 0.8 mg/L, it is not advisable to exceed 0.6 mg/L copper. Remove with activated carbon