Plant Extracts Have Curative Effect On Inflammatory Bowel Disease
There is a certain relationship between ulcerative colitis and colon cancer. The people with ulcerative colitis significantly higher risk of colon cancer. These extracts whether direct help, or may delay the onset of colon cancer colon cancer symptoms of colitis patients, we do not know the answer. This is what we want to study reasons.
Mammalian cell screening platform can be screened out nearly 3000 kinds of anti-inflammatory plant extracts. Phenethyl isothiocyanate plant extracts are proved to have the anti-inflammatory effects in the extract. The PEITC exist in brassica napus species, including cabbage, cauliflower, watercress and broccoli. Highland cress, also known as mountain mustard, one for herbs in salads, soups and side dishes, is to study a rich source of PEITC plants. Study anti-inflammatory activities of this plant, scientists have studied its anti-cancer properties.
The scientists tested the substance in a mouse model of long-established and widely used. This plant not only can reduce the clinical symptoms of ulcerative colitis such as diarrhea and bloody stool, but also ease the colon tissue and epithelial damage. Weight loss is the main symptoms of colitis, this plant was also effective. Although mammalian model is often used preliminary test compounds for human consumption, but the results are not always consistent with human. Inflammatory bowel disease is a group of chronic and recurrent inflammation in the gut, the annual incidence of approximately 200 million. The two common types of IBD are Crohn's disease and ulcerative colitis. Study the mechanism of this plant treatment of IBD, it can cut many of the genes upregulated in the colitis patients. Description of these plants can function in cells, reducing the number of cellular components, such as special protein in a large number of colitis patients, in which a protein is a novel transcription factor. Transcription factor is one of the proteome to read and translate DNA genetic blueprint. In the future, researchers will study on these pharmaceutical raw materials and the extracted compounds combat and relieve foe colon cancer.
The only reason for researchers study in colon cancer special items is its similarity between ulcerative colitis and colon cancer. Colon cancer is easy to prevent, but because of the commonly late diagnosis, it has higher mortality rates. Human beings have been started in eating vegetables containing PEITC for a long time. It has a long history without side effects. The test dose is significantly higher than the amount of usually eating vegetables. The researchers make a number of safety tests and find that that dose is safe to mammals. The researchers do not have plans to test in humans. They believe that, in order to make these extracts as a new drug or treatment methods meeting for human needs, it should have further studies.
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