Zoloft: The Treatment for Major Depression

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One of the most recommended antidepressant in the United States, Zoloft, is manufactured by the leading global pharmaceutical company - Pfizer Inc. It is the used to treat numerous neurological problems most importantly major depression which affects 19 million adults in the United States alone. On the other hand, administering the drug requires precautions as Zoloft side effects are pretty common.

A depressive disorder is a syndrome (group of symptoms) reflecting a sad and/or irritable mood beyond normal sadness or grief. The feeling of sadness is more extreme and lasts longer that it already preoccupies life's normal activities.

The following are signs and symptoms of depression:
- Difficulty concentration, remembering details, and making decisions
- Fatigue and decreased energy
- Feelings of guilt, worthlessness, and/or hopelessness
- Feelings of pessimism
- Insomnia, early-morning wakefulness, or excessive sleeping
- Irritability, restlessness
- Loss of interest in activities or hobbies once pleasurable, including sex
- Increase or loss in appetite
- Persistent aches or pains, headaches, cramps, or digestive problems unrelieved with treatment
- Persistent sadness, anxiety or "empty" feelings
- Suicidal thoughts and/or suicide attempts

Feeling sad, lonely or depressed at times is definitely normal to anyone especially as a reaction to loss, struggles in life, or a fractioned self-esteem. But if it becomes disturbing affecting your normally enjoyable life, perhaps It's time that you need to seek the advice of your physician.

Untreated symptoms of clinical or major depression may worsen throughout time and cause suffering and may even be life-threatening. At least 10% of people with major depression ended up in committing suicide.
The medical treatment of choice, usually along with other therapies, is an antidepressant. The SSRIs or selective serotonin reuptake inhibitors is the most popular group of antidepressants. This type of antidepressant includes Zoloft which is also known by its generic name sertraline hydrochloride.

SSRIs work by acting on chemical messengers or neurotransmitters, particularly the serotonin, which play a vital role in the communication between brain cells. A lot of neurological problems may develop when the number of serotonin plummets. Zoloft inhibits serotonin reuptake or absorption to keep adequate amount of serotonin for relay of chemical signals.

To find out if you are suffering from major depression you need to seek medical attention. Furthermore, taking antidepressants like Zoloft also need the conference with your doctor as taking the drug involves apparent risks. Major depression is a serious illness and likewise treatment must also be taken seriously.
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