HIV and AIDS: Who Is Affected-Topic Overview HIV and AIDS can affect anyone. Worldwide, an estimated 33 million people are living with HIV or AIDS.¹ In the United States, more than a million people are infected with HIV.² Many of these people do not know they are infected.

Since the use of antiretroviral therapy (ART) became widespread in 1996, the incidence of AIDS has decreased. Factors responsible for the decline in the incidence of new AIDS cases include:³

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HIV, AIDS, and Mycobacterium Avium Complex

Mycobacterium avium complex (MAC) is a group of bacteria that are related to tuberculosis. These germs are very common in food, water, and soil. Almost everyone has them in their bodies. If you have a strong immune system, they don't cause problems. But they can cause serious illness in people with HIV (human immunodeficiency virus). With the right combination of medications, however, you can prevent or treat MAC. In some cases, you may need lifelong therapy.

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• Fewer people are becoming infected with HIV today than in the early 1980s.
• Improved treatments for HIV infection. ART slows the rate at which HIV multiplies in the body. This helps keep a person's immune system healthy longer, which may slow the rate at which opportunistic diseases (such as pneumonia) develop.
• More effective treatments are available to prevent HIV-related infections.

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