Rothia dentocariosa Endocarditis
Rothia dentocariosa Endocarditis
Rothia dentocariosa is a gram-positive rod found commonly as part of the normal flora of the mouth. It rarely causes clinical disease. Subacute infective endocarditis has been the most commonly reported R dentocariosa infection, and extracardiac complications occur frequently. Solitary intracranial hemorrhages have been reported in two cases. We describe the first case of infective endocarditis complicated by the sequential and unusually prolonged development of multiple new intracranial hemorrhages.
Rothia dentocariosa, a pleomorphic gram-positive rod, is a common inhabitant of the nose and throat. It was originally isolated from dental plaque and caries by Onishi in 1949. Because of its similarity with Actinomyces and Nocardia, it underwent several taxonomic changes until 1967, when Georg and Brown proposed the creation of the new genus Rothia. It has been generally regarded as an organism of low virulence, though its pathogenicity in the mouse model was proven in 1969. However, over the past three decades several cases of clinical infections due to R dentocariosa have been reported, the most common being infective endocarditis. Extracardiac complications occurred in more than half of the patients with R dentocariosa endocarditis, including two patients with solitary intracranial hemorrhages. We describe a case of R dentocariosa endocarditis complicated by the sequential, prolonged development of multiple new intracranial hemorrhages and successfully treated with antibiotics.
Rothia dentocariosa is a gram-positive rod found commonly as part of the normal flora of the mouth. It rarely causes clinical disease. Subacute infective endocarditis has been the most commonly reported R dentocariosa infection, and extracardiac complications occur frequently. Solitary intracranial hemorrhages have been reported in two cases. We describe the first case of infective endocarditis complicated by the sequential and unusually prolonged development of multiple new intracranial hemorrhages.
Rothia dentocariosa, a pleomorphic gram-positive rod, is a common inhabitant of the nose and throat. It was originally isolated from dental plaque and caries by Onishi in 1949. Because of its similarity with Actinomyces and Nocardia, it underwent several taxonomic changes until 1967, when Georg and Brown proposed the creation of the new genus Rothia. It has been generally regarded as an organism of low virulence, though its pathogenicity in the mouse model was proven in 1969. However, over the past three decades several cases of clinical infections due to R dentocariosa have been reported, the most common being infective endocarditis. Extracardiac complications occurred in more than half of the patients with R dentocariosa endocarditis, including two patients with solitary intracranial hemorrhages. We describe a case of R dentocariosa endocarditis complicated by the sequential, prolonged development of multiple new intracranial hemorrhages and successfully treated with antibiotics.
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